rapchic skrev:Jag har ju själv blivit mycket, mycket bättre när det gäller min AS sen jag fick diagnosen. Däremot har jag de senaste ca 2 åren gått bakåt pga min värk (och min värk blir värre av tex gluten).

A vegan diet free of gluten improves the signs and symptoms of rheumatoid arthritis: the effects on arthritis correlate with a reduction in antibodies to food antigens.

Department of Rheumatology, Karolinska Institutet at Huddinge University Hospital, Stockholm, Sweden.

Abstract
OBJECTIVE:
Whether food intake can modify the course of rheumatoid arthritis (RA) is an issue of continued scientific and public interest. However, data from controlled clinical trials are sparse. We thus decided to study the clinical effects of a vegan diet free of gluten in RA and to quantify the levels of antibodies to key food antigens not present in the vegan diet.

METHODS:
Sixty-six patients with active RA were randomized to either a vegan diet free of gluten (38 patients) or a well-balanced non-vegan diet (28 patients) for 1 yr. All patients were instructed and followed-up in the same manner. They were analysed at baseline and after 3, 6 and 12 months, according to the response criteria of the American College of Rheumatology (ACR). Furthermore, levels of antibodies against gliadin and beta-lactoglobulin were assessed and radiographs of the hands and feet were performed.

RESULTS:
Twenty-two patients in the vegan group and 25 patients in the non-vegan diet group completed 9 months or more on the diet regimens. Of these diet completers, 40.5% (nine patients) in the vegan group fulfilled the ACR20 improvement criteria compared with 4% (one patient) in the non-vegan group. Corresponding figures for the intention to treat populations were 34.3 and 3.8%, respectively. The immunoglobulin G (IgG) antibody levels against gliadin and beta-lactoglobulin decreased in the responder subgroup in the vegan diet-treated patients, but not in the other analysed groups. No retardation of radiological destruction was apparent in any of the groups.

CONCLUSION:
The data provide evidence that dietary modification may be of clinical benefit for certain RA patients, and that this benefit may be related to a reduction in immunoreactivity to food antigens eliminated by the change in diet.

Gluten-free vegan diet induces decreased LDL and oxidized LDL levels and raised atheroprotective natural antibodies against phosphorylcholine in patients with rheumatoid arthritis: a randomized study.

Rheumatology Unit, Karolinska Institutet at Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden.

Abstract
INTRODUCTION:
The purpose of this study was to investigate the effects of vegan diet in patients with rheumatoid arthritis (RA) on blood lipids oxidized low-density lipoprotein (oxLDL) and natural atheroprotective antibodies against phosphorylcholine (anti-PCs).

METHODS:
Sixty-six patients with active RA were randomly assigned to either a vegan diet free of gluten (38 patients) or a well-balanced non-vegan diet (28 patients) for 1 year. Thirty patients in the vegan group completed more than 3 months on the diet regimen. Blood lipids were analyzed by routine methods, and oxLDL and anti-PCs were analyzed by enzyme-linked immunosorbent assay. Data and serum samples were obtained at baseline and after 3 and 12 months.

RESULTS:
Mean ages were 50.0 years for the vegan group and 50.8 years for controls. Gluten-free vegan diet induced lower body mass index (BMI) and low-density lipoprotein (LDL) and higher anti-PC IgM than control diet (p < 0.005). In the vegan group, BMI, LDL, and cholesterol decreased after both 3 and 12 months (p < 0.01) and oxLDL after 3 months (p = 0.021) and trendwise after 12 months (p = 0.090). Triglycerides and high-density lipoprotein did not change. IgA anti-PC levels increased after 3 months (p = 0.027) and IgM anti-PC levels increased trendwise after 12 months (p = 0.057). There was no difference in IgG anti-PC levels. In the control diet group, IgM anti-PC levels decreased both after 3 and 12 months (p < 0.01). When separating vegan patients into clinical responders and non-responders at 12 months, the effects on oxLDL and anti-PC IgA were seen only in responders (p < 0.05).

CONCLUSION:
A gluten-free vegan diet in RA induces changes that are potentially atheroprotective and anti-inflammatory, including decreased LDL and oxLDL levels and raised anti-PC IgM and IgA levels.

KourosGould skrev:Om vi tar grupptrycket t.ex. Jag skulle inte vilja styras av en grupp, då känns det som att jag tummar på min fria vilja. Många NT vill tydligen styras av andra i en normens frivilliga diktatur och många NT plågas dagligen av att leva i den men har ändå ett konstigt behov av att leva så. Den plågan slipper jag och det tror jag beror en hel del på vissa av de personlighetsdrag som gjort att jag fått diagnosen AS.

dasunbedingte skrev:

rapchic skrev:Jag har ju själv blivit mycket, mycket bättre när det gäller min AS sen jag fick diagnosen. Däremot har jag de senaste ca 2 åren gått bakåt pga min värk (och min värk blir värre av tex gluten).

Glutenfri kost kan lindra smärtan vid RA, vilket dessa studier från Karolinska Institutet påvisade 2001 & 2008 (finns dock mer uppdaterade studier att tillgå), så det är ingen placebo! Jag märker att min migrän blir mindre frekvent med totalt uteslutande av gluten samt att mina leder är mindre benägna att inflammeras efter hård terränglöpning (av uteslutande av gluten och förtäring av växtbaserad kost, sistnämnda finns inga helt säkra studier på, så inget jag rekommenderar av de skälen) - mer inslag av rå kost också underlättar (dock finns inga säkra studier på sistnämnda, så inget jag rekommenderar folk):